KF 18259
KF 18259 is a 5-HT3-receptor antagonist. KF 18259 inhibits the wrap-restraint stress-induced propulsive motility of the proximal and distal colon[1].
Product Specifications
CAS Number
[139094-48-7]
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Others
Smiles
CN([C@@H](CC1)C2)[C@H]1C[C@@H]2OC(C(C3=CC=CC=C3N4CC(C)C)=CC4=O)=O.Cl
Molecular Formula
C22H29ClN2O3
Molecular Weight
404.93
References & Citations
[1]Kishibayashi N, et al. Pharmacological properties of KF18259, a novel 5-HT3-receptor antagonist, in rats: inhibition of the distal colonic function. Jpn J Pharmacol. 1993 Dec;63 (4) :495-502.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT3 Receptor
Curated Selection
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