MDL 105212A

MDL 105212A is a potent and orally active nonpeptide neurokinin receptor (NK-1/NK-2) tachykinin receptor antagonist. MDL 105212A can be used for the researches of inflammation, immunology and neurological disease, such as asthma[1].

Product Specifications

CAS Number

[167261-60-1]

UNSPSC

12352005

Target

Neurokinin Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

NC(C(CC1)(C2=CC=CC=C2)CCN1CC[C@@]3(C4=CC(Cl)=C(Cl)C=C4)CN(C(C5=CC(OC)=C(OC)C(OC)=C5)=O)CC3)=O.Cl

Molecular Formula

C34H40Cl3N3O5

Molecular Weight

677.06

References & Citations

[1]Kudlacz EM, et al. In vitro and in vivo characterization of MDL 105,212A, a nonpeptide NK-1/NK-2 tachykinin receptor antagonist. J Pharmacol Exp Ther. 1996 May;277 (2) :840-51.