U-75875

U-75875 is a HIV-1 protease inhibitor. U-75875 can block Gag-Pol protein processing and viral maturation and replication. U-75875 can be used for the research of infection[1][2].

Product Specifications

CAS Number

[112190-24-6]

UNSPSC

12352005

Target

HIV Protease

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

O=C(NCC1=CC=CC=N1)[C@H]([C@@H](C)CC)NC([C@H](C(C)C)[C@@H](O)[C@H](O)[C@H](CC2CCCCC2)NC([C@H](CC3=CN=CN3)NC(COC4=CC=CC5=C4C=CC=C5)=O)=O)=O

Molecular Formula

C45H61N7O7

Molecular Weight

812.01

References & Citations

[1]Martin LN, et al. Effects of U-75875, a peptidomimetic inhibitor of retroviral proteases, on simian immunodeficiency virus infection in rhesus monkeys. Antimicrob Agents Chemother. 1994 Jun;38 (6) :1277-83.|[2]Peterson PK, et al. Anti-human immunodeficiency virus type 1 activities of U-90152 and U-75875 in human brain cell cultures. Antimicrob Agents Chemother. 1994 Oct;38 (10) :2465-8.