WR 151327

WR 151327 is an orally active radiation and chemoprotection protector. WR 151327 can suppress expression of HIV. WR 151327 can be used for the researches of infection and cancer[1][2][3].

Product Specifications

CAS Number

[82147-31-7]

UNSPSC

12352211

Target

Bacterial; HIV

Related Pathways

Anti-infection

Field of Research

Cancer; Infection

Smiles

CNCCCNCCCSP(O)(O)=O

Molecular Formula

C7H19N2O3PS

Molecular Weight

242.28

References & Citations

[1]Ledney GD, et al. WR-151327 increases resistance to Klebsiella pneumoniae infection in mixed-field- and gamma-photon-irradiated mice. Int J Radiat Biol. 2000 Feb;76 (2) :261-71.|[2]Kalebic T, et al. Organic thiophosphate WR-151327 suppresses expression of HIV in chronically infected cells. AIDS Res Hum Retroviruses. 1994 Jun;10 (6) :727-33.|[3]Green D, et al. Preclinical evaluation of WR-151327: an orally active chemotherapy protector. Cancer Res. 1994 Feb 1;54 (3) :738-41.