Tramadol N-oxide
Tramadol N-oxide (T-N-O) (RWJ 38705) is an analgesic. Tramadol N-oxide sproduces dose-related, long-lasting antinociception in the mouse abdominal irritant, 48 °C hot-plate, 55 °C hot-plate, and tail-flick tests. Tramadol N-oxide has negligible affinity for opioid mu (Ki = 38.5 μM) and delta or kappa receptors (Ki > 100 μM) . Tramadol N-oxide can be used for the study of analgesic effect[1].
Product Specifications
CAS Number
147441-56-3
Product Name Alternative
RWJ-38705
UNSPSC
12352005
Target
Opioid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O[C@@]1(C2=CC(OC)=CC=C2)[C@H](CCCC1)CN(C)(C)=O
Molecular Formula
C16H25NO3
Molecular Weight
279.37
References & Citations
[1]Raffa RB, et al. Unexpected antinociceptive effect of the N-oxide (RWJ 38705) of tramadol hydrochloride. J Pharmacol Exp Ther. 1996 Sep;278 (3) :1098-104.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
μ Opioid Receptor/MOR
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNCB2245-100 1x 100 µL
HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (CPTC-HSPD1-1), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
Dx45660 50 Devices
Stool Nucleic Acid Collection and Preservation Devices Dx
Sign In for Pricing
View Details ![S100A9 Mouse Monoclonal Antibody [Clone ID: CF-557]](https://cdn.genprice.uk/products/937/68dd189d061270361e8fd119/imageurl/am31839pu-n.webp)
AM31839PU-N 200 µg
S100A9 Mouse Monoclonal Antibody [Clone ID: CF-557]
Sign In for Pricing
View Details 
