PNU-103657
PNU-103657 (Compound 13) is an orally active reverse transcriptase inhibitor (IC50 = 0.51 μM (WT) ) . PNU-103657 has antiviral activity. PNU-103657 can be used in research on infections and immune system diseases such as HIV infection[1].
Product Specifications
CAS Number
179556-43-5
UNSPSC
12352005
Target
HIV; Reverse Transcriptase
Related Pathways
Anti-infection
Field of Research
Infection; Inflammation/Immunology
Smiles
O=C(N1CCC(CC1)N(C)C2=NC=CC=C2CC(C)C)C3=CC4=C(N3)C=CC(NS(=O)(C)=O)=C4
Molecular Formula
C25H33N5O3S
Molecular Weight
483.63
References & Citations
[1]Genin MJ, et al. Synthesis and structure-activity relationships of the (alkylamino) piperidine-containing BHAP class of non-nucleoside reverse transcriptase inhibitors: effect of 3-alkylpyridine ring substitution. J Med Chem. 1999 Oct 7;42 (20) :4140-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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