PNU-103657

PNU-103657 (Compound 13) is an orally active reverse transcriptase inhibitor (IC50 = 0.51 μM (WT) ) . PNU-103657 has antiviral activity. PNU-103657 can be used in research on infections and immune system diseases such as HIV infection[1].

Product Specifications

CAS Number

[179556-43-5]

UNSPSC

12352005

Target

HIV; Reverse Transcriptase

Related Pathways

Anti-infection

Field of Research

Infection; Inflammation/Immunology

Smiles

O=C(N1CCC(CC1)N(C)C2=NC=CC=C2CC(C)C)C3=CC4=C(N3)C=CC(NS(=O)(C)=O)=C4

Molecular Formula

C25H33N5O3S

Molecular Weight

483.63

References & Citations

[1]Genin MJ, et al. Synthesis and structure-activity relationships of the (alkylamino) piperidine-containing BHAP class of non-nucleoside reverse transcriptase inhibitors: effect of 3-alkylpyridine ring substitution. J Med Chem. 1999 Oct 7;42 (20) :4140-9.