KF 22678
KF 22678 is a thioester derivative of leinamycin. KF 22678 exhibits a broad antitumor spectrum against human carcinoma xenografts, including lung, colon, ovary, and prostate cancers. KF 22678 can be used for the study of cancer[1].
Product Specifications
CAS Number
[186643-40-3]
UNSPSC
12352005
Target
Drug Derivative
Related Pathways
Others
Field of Research
Cancer
Smiles
CC1=C(OC(O1)=O)CSC([C@](O)([C@@]2(C3)S(N([C@@H](C4=NC(/C=C\C=C\C([C@H](O[C@]5([H])CCCCO5)/C=C(C)\CC2)=O)=CS4)C)C3=O)=O)C)=O
Molecular Formula
C32H38N2O10S3
Molecular Weight
706.85
References & Citations
[1]Ashizawa T, et al. Antitumor activity of KF22678, a novel thioester derivative of leinamycin. Anticancer Drugs. 1999 Oct;10 (9) :829-36.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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