PD 155080
PD 155080 is a selective endothelin A receptor (ETA receptor) antagonist. PD 155080 reduces coronary resistance in the isolated rat heart model. PD 155080 improves myocardial systolic function and diastolic function in the ischemia/reperfusion model. PD 155080 can be used for the study of cardiovascular diseases[1].
Product Specifications
CAS Number
162412-71-7
UNSPSC
12352005
Target
Endothelin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
O=C(O[Na])/C(C1=CC=C(OCO2)C2=C1)=C(CC3=CC=CC=C3)/C(C4=CC=C(OC)C=C4)=O
Molecular Formula
C25H19NaO6
Molecular Weight
438.40
References & Citations
[1]Brunner F, et al. Role of ET (B) receptors in local clearance of endothelin-1 in rat heart: studies with the antagonists PD 155080 and BQ-788. FEBS Lett. 1996 Nov 4;396 (2-3) :238-42.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ETA
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