GI-129471
GI-129471 is a MMP inhibitor. GI-129471 exhibits inhibitory activity against cancer cell invasion. GI-129471 can completely block the enhanced production of IgE and IgG1 by mouse B cells induced by rat mast cell protease-I (RMCP-I) . GI-129471 can be used for the study of cancer and mast cell chymase-regulated immunological processes[1][2].
Product Specifications
CAS Number
130370-59-1
UNSPSC
12352005
Target
MMP
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Smiles
ONC([C@@H](CSC1=CC=CC=C1)[C@@H](CC(C)C)C(N[C@H](C(NC)=O)CC2=CC=CC=C2)=O)=O
Molecular Formula
C25H33N3O4S
Molecular Weight
471.61
References & Citations
[1]Kempen I, et al. 3-Bromophenyl 6-acetoxymethyl-2-oxo-2H-1-benzopyran-3-carboxylate inhibits cancer cell invasion in vitro and tumour growth in vivo. Br J Cancer. 2003 Apr 7;88 (7) :1111-8. |[2]Yoshikawa T, et al. Rat mast cell protease-I enhances immunoglobulin E production by mouse B cells stimulated with interleukin-4. Immunology. 2001 Nov;104 (3) :333-40.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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