CEB-1604
CEB-1604 is an NMDA receptor antagonist. CEB-1604 inhibits NMDA-induced currents in oocytes transfected with NMDA receptor isoforms (NR1/NR2A, NR1/NR2B, NR1/NR2C, NR1/NR2D) with IC50 values ranging from 5 to 12 μM. CEB-1604 abolishes NMDA-dependent epileptiform discharges in rat cortical wedge preparations and reduces the depolarizing effects of NMDA. CEB-1604 can be used in the research field of neurological damage diseases[1].
Product Specifications
CAS Number
287173-08-4
UNSPSC
12352005
Target
IGluR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
NCC1(C2=CC(C)=CC=C2)[C@H]3C[C@H](C4)C[C@@H]1C[C@H]4C3
Molecular Formula
C18H25N
Molecular Weight
255.40
References & Citations
[1]Scriabine A, et al. Meeting Reports: Thirty-first Annual Meeting of Society for Neuroscience San Diego, CA November 10–15, 2001. CNS Drug Reviews. 2002, 8 (2) : 193-200
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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