Dilopetine (citrate)
Dilopetine citrate is an inhibitor of substance P release. Dilopetine citrate dose-dependently reduces the vocalizing of isolated guinea pig pups. Dilopetine citrate shows good activity as an antidepressant[1][2].
Product Specifications
CAS Number
247046-64-6
Product Name Alternative
E-6006 (citrate)
UNSPSC
12352005
Target
Neurokinin Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
OC(CC(C(O)=O)(O)CC(O)=O)=O.CN(C)CCOC(C1=CC=CS1)C2=CC=NN2C
Molecular Formula
C19H27N3O8S
Molecular Weight
457.50
References & Citations
[1]Gómez-Gomar A, et al. Enantioseparation of basic pharmaceutical compounds by capillary electrophoresis using sulfated cyclodextrins. Application to E-6006, a novel antidepressant. J Chromatogr A. 2003 Mar 21;990 (1-2) :91-8.|[2]Hennessy MB, et al. Effects of a novel potential antidepressant on the behavior and cortisol levels of isolated guinea pig pups. Pharmacol Biochem Behav. 2001 Jul-Aug;69 (3-4) :527-33.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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