SIB 1663
SIB 1663 is a conformationally restricted analog of nicotine. SIB-1663 selectively activatedα2β4 and α4β4 human recombinant neuronal nAChRs. SIB 1663 can increase DA and NE release. SIB 1663 can be used for the research of neurological disease[1].
Product Specifications
CAS Number
[179064-11-0]
UNSPSC
12352005
Target
NAChR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
COC1=NC=C2C(CCC3CCNC23)=C1
Molecular Formula
C12H16N2O
Molecular Weight
204.27
References & Citations
[1]Rao TS, et al. Pharmacological characterization of SIB-1663, a conformationally rigid analog of nicotine. Brain Res. 2004 Apr 2;1003 (1-2) :42-53.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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