Modimelanotide
Modimelanotide (ABT-719) is an α-melanocyte-stimulating hormone analog. Modimelanotide has high specific binding ability to melanocortin receptors (MCR1, 3, 4, 5) . Modimelanotide possesses anti-inflammatory and organ-protective effects. Modimelanotide can be used in the research of diseases such as acute kidney injury[1][2].
Product Specifications
CAS Number
926277-68-1
Product Name Alternative
ABT-719; AP-214
UNSPSC
12352005
Target
Melanocortin Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Inflammation/Immunology
Smiles
O=C(C)N[C@@H](CCCCN)C(N[C@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@H](CCCCN)C(N[C@@H](CO)C(N[C@H](CC1=CC=C(O)C=C1)C(N[C@@H](CO)C(N[C@H](CCSC)C(N[C@@H](CCC(O)=O)C(N[C@H](CC2=CN=CN2)C(N[C@H](C(N[C@H](CCCNC(N)=N)C(N[C@@H](CC3=CNC4=C3C=CC=C4)C(NCC(N[C@@H](CCCCN)C(N5[C@H](C(N[C@@H](C(C)C)C(N)=O)=O)CCC5)=O)=O)=O)=O)=O)CC6=CC=CC=C6)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C113H181N33O25S
Molecular Weight
2433.92
References & Citations
[1]Ruiz J. Transferable Mechanisms of Quinolone Resistance from 1998 Onward. Clin Microbiol Rev. 2019 Aug 14;32 (4) :e00007-19.|[2]McCullough PA, et al. ABT-719 for the Prevention of Acute Kidney Injury in Patients Undergoing High-Risk Cardiac Surgery: A Randomized Phase 2b Clinical Trial. J Am Heart Assoc. 2016 Aug 20;5 (8) :e003549.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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