CKD-711
CKD-711 is an orally active aminooligosaccharide α-glucosidase inhibitor with an IC50 of 78 μg/mL. CKD-711 also inhibits porcine intestinal maltase and sucrose with IC50 values of 2.5 and 0.5 μg/mL. CKD-711 shows selective antibacterial activity against Comamonas terrigena. CKD-711 can be used for the researches of infection and metabolic disease, such as diabetes[1].
Product Specifications
CAS Number
445010-62-8
UNSPSC
12352005
Target
Bacterial; Glycosidase
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection; Metabolic Disease
Smiles
OC[C@]12[C@@H]([C@@H]([C@H](O)[C@@H](O)[C@@H]2O)N[C@]3([H])[C@H](O[C@H](O[C@]4([H])[C@H](O[C@H](O[C@@]([C@H](O)CO)([H])[C@H](O)[C@@H](O)C=O)[C@H](O)[C@H]4O)CO)[C@H](O)[C@H]3O)CO)O1
Molecular Formula
C25H43NO20
Molecular Weight
677.60
References & Citations
[1]Kwon YI, et al. Novel alpha-glucosidase inhibitors, CKD-711 and CKD-711a produced by Streptomyces sp. CK-4416. II. Biological properties. J Antibiot (Tokyo) . 2002 May;55 (5) :462-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Glucosidase
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