Amesergide
Amesergide is a serotonin (5-HT1C/2) antagonist. Amesergide can result in a reduction of progeny body weight gains in maternal animals. Amesergide can be studied in research on depression[1][2].
Product Specifications
CAS Number
[121588-75-8]
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
CC(N1C2=C3C([C@]4([H])[C@@](N(C[C@@H](C4)C(NC5CCCCC5)=O)C)([H])CC3=C1)=CC=C2)C
Molecular Formula
C25H35N3O
Molecular Weight
393.56
References & Citations
[1]Seyler, D. E., et al., (1993) . Effects of the serotonin antagonist amesergide on reproduction in female rats. Reproductive toxicology (Elmsford, N.Y.), 7 (6), 607-612. |[2]Kelich, S. L., et al., (1995) . Developmental toxicity of amesergide administered by gavage to CD rats and New Zealand white rabbits. Fundamental and applied toxicology : official journal of the Society of Toxicology, 27 (2), 247-251.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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