AZT-P-ddI

AZT-P-ddI is an antiviral heterodimer composed of Zidovudine (AZT) (HY-17413) and Didanosine (ddI) (HY-B0249) . AZT-P-ddI shows inhibitory effect against HIV-1 with an EC50 of 0.14 nM. AZT-P-ddI can be used for the research of infection[1].

Product Specifications

CAS Number

[121135-53-3]

Product Name Alternative

IVX-E-59

UNSPSC

12352005

Target

HIV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C1C2=C(NC=N1)N([C@@H]3O[C@@H](CC3)COP(OC[C@@H]4[C@H](C[C@H](N5C(NC(C(C)=C5)=O)=O)O4)N=[N+]=[N-])(O)=O)C=N2

Molecular Formula

C20H24N9O9P

Molecular Weight

565.43

References & Citations

[1]Schinazi RF, et al. Activities of 3'-azido-3'-deoxythymidine nucleotide dimers in primary lymphocytes infected with human immunodeficiency virus type 1. Antimicrob Agents Chemother. 1990 Jun;34 (6) :1061-7.