FK 838
FK 838 is an adenosine subtype-1 receptor antagonist with potent diuretic activity. FK 838 can be used for the research of cardiovascular disease, such as hypertension [1].
Product Specifications
CAS Number
[131185-37-0]
UNSPSC
12352005
Target
Adenosine Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
OC(CCCN1N=C(C=CC1=O)C2=C(C=CC=C3)N3N=C2C4=CC=CC=C4)=O
Molecular Formula
C21H18N4O3
Molecular Weight
374.39
References & Citations
[1]Uehara Y, et al. A new adenosine subtype-1 receptor antagonist, FK-838, attenuates salt-induced hypertension in Dahl salt-sensitive rats. Am J Hypertens. 1995 Dec;8 (12 Pt 1) :1189-99.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Curated Selection
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