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FK 838

FK 838 is an adenosine subtype-1 receptor antagonist with potent diuretic activity. FK 838 can be used for the research of cardiovascular disease, such as hypertension [1].

Product Specifications

CAS Number

[131185-37-0]

UNSPSC

12352005

Target

Adenosine Receptor

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Smiles

OC(CCCN1N=C(C=CC1=O)C2=C(C=CC=C3)N3N=C2C4=CC=CC=C4)=O

Molecular Formula

C21H18N4O3

Molecular Weight

374.39

References & Citations

[1]Uehara Y, et al. A new adenosine subtype-1 receptor antagonist, FK-838, attenuates salt-induced hypertension in Dahl salt-sensitive rats. Am J Hypertens. 1995 Dec;8 (12 Pt 1) :1189-99.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Curated Selection

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