CI-988 (meglumin)

CI-988 meglumin is a cholecystokinin 2 receptor (CCK2R) antagonist. CI-988 meglumin prevents the gastrin-mediated protection of the heart with ischemia/reperfusion injury[1].

Product Specifications

CAS Number

[130404-91-0]

Product Name Alternative

PD134308 (meglumin)

UNSPSC

12352005

Target

Cholecystokinin Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Smiles

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNC.OC(CCC(N[C@H](C1=CC=CC=C1)CNC([C@](CC2=CNC3=C2C=CC=C3)(C)NC(OC4[C@H]5C[C@H](C6)C[C@@H]4C[C@H]6C5)=O)=O)=O)=O

Molecular Formula

C42H59N5O11

Molecular Weight

809.94

References & Citations

[1]Yang X, et al. Gastrin Protects Against Myocardial Ischemia/Reperfusion Injury via Activation of RISK (Reperfusion Injury Salvage Kinase) and SAFE (Survivor Activating Factor Enhancement) Pathways. J Am Heart Assoc. 2018 Jul 12;7 (14) :e005171.