KU-2285
KU-2285 is an orally active fluorinated 2-nitroimidazole hypoxic cell radiosensitizer. KU-2285 has higher lipophilicity, superior sensitizing activity to Etanidazole , and lower neurotoxicity. KU-2285 can be used in research related to tumor diagnosis[1][2].
Product Specifications
CAS Number
121077-11-0
UNSPSC
12352005
Target
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Cancer
Smiles
O=C(NCCO)C(F)(F)CN1C=CN=C1[N+]([O-])=O
Molecular Formula
C8H10F2N4O4
Molecular Weight
264.19
References & Citations
[1]Sasai K, et al. A fluorinated 2-nitroimidazole, KU-2285, as a new hypoxic cell radiosensitizer. Int J Radiat Oncol Biol Phys. 1991 Jun;20 (6) :1249-54.|[2]Shibamoto Y, et al. A phase I study of a hypoxic cell sensitizer KU-2285 in combination with conventional radiotherapy. Radiother Oncol. 1996 Jul;40 (1) :55-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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