MS-322
MS-322 is an orally active centrally acting muscle relaxant. MS-322 can dose-dependently inhibit spinal reflex potentials, reduce neuronal excitability and muscle afferent discharges, and so on in rats. In addition, MS-322 has relatively weak inhibitory effects on other central nervous system pathways and no effect on the neuromuscular junction[1][2].
Product Specifications
CAS Number
144576-50-1
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Neurological Disease
Smiles
CC[C@H](CN1CCCC1)C(C2=CC(C3=CC=CC=C3)=NO2)=O.Cl
Molecular Formula
C18H23ClN2O2
Molecular Weight
334.84
References & Citations
[1]Otsu T, et al. Muscle relaxant action of MS-322, a new centrally acting muscle relaxant, in rats. Gen Pharmacol. 1998 Mar;30 (3) :393-8.|[2]Otsu T, et al. Pharmacological properties of the new centrally acting muscle relaxant (R) - (+) -3-phenyl-5-[2- (1-pyrrolidinylmethyl) butyryl] isoxazole hydrochloride. Arzneimittel-forschung, 1997, 47 (6) : 706-709.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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