ONO-4007

ONO-4007 is an antitumor lipid A analogue. ONO-4007 exhibits strong antitumor activity in several animal models via intratumoral production of tumor necrosis factor-alpha production (TNF-α) . ONO-4007 can be used for the research of cancer[1].

Product Specifications

CAS Number

[152646-95-2]

UNSPSC

12352005

Target

TNF Receptor

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C[C@H](NC(C[C@@H](OC(CCCCCCCCC1=CC=CC=C1)=O)CCCCCCCCCCC)=O)[C@@H](OC(CCCCCCCCC2=CC=CC=C2)=O)[C@H](OS(=O)(O[Na])=O)[C@@H](CO)O

Molecular Formula

C50H78NNaO12S

Molecular Weight

940.21

References & Citations

[1]Matsumoto N, et al. ONO-4007, an antitumor lipid A analog, induces tumor necrosis factor-alpha production by human monocytes only under primed state: different effects of ONO-4007 and lipopolysaccharide on cytokine production. J Pharmacol Exp Ther. 1998 Jan;284 (1) :189-95.