ONO-4007
ONO-4007 is an antitumor lipid A analogue. ONO-4007 exhibits strong antitumor activity in several animal models via intratumoral production of tumor necrosis factor-alpha production (TNF-α) . ONO-4007 can be used for the research of cancer[1].
Product Specifications
CAS Number
[152646-95-2]
UNSPSC
12352005
Target
TNF Receptor
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C[C@H](NC(C[C@@H](OC(CCCCCCCCC1=CC=CC=C1)=O)CCCCCCCCCCC)=O)[C@@H](OC(CCCCCCCCC2=CC=CC=C2)=O)[C@H](OS(=O)(O[Na])=O)[C@@H](CO)O
Molecular Formula
C50H78NNaO12S
Molecular Weight
940.21
References & Citations
[1]Matsumoto N, et al. ONO-4007, an antitumor lipid A analog, induces tumor necrosis factor-alpha production by human monocytes only under primed state: different effects of ONO-4007 and lipopolysaccharide on cytokine production. J Pharmacol Exp Ther. 1998 Jan;284 (1) :189-95.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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