Galarubicin (hydrochloride)
Galarubicin hydrochloride (DA 125) is a novel Anthracycline derivative. Galarubicin hydrochloride shows high-affinity DNA binding and topoisomerase II inhibitory activities. Galarubicin hydrochloride induces Apoptosis. Galarubicin hydrochloride exerts cytotoxicity via JNK pathway. Galarubicin hydrochloride can be used in the research of hepatocellular carcinoma[1].
Product Specifications
CAS Number
140637-82-7
Product Name Alternative
DA 125
UNSPSC
12352005
Target
Apoptosis; DNA Alkylator/Crosslinker; Drug Derivative; JNK; Topoisomerase
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; MAPK/ERK Pathway; Others
Field of Research
Cancer
Smiles
F[C@H]([C@@H]([C@H](O)[C@H](C)O1)O)[C@]1([H])O[C@@H]2C3=C(O)C(C(C4=C(OC)C=CC=C4C5=O)=O)=C5C(O)=C3C[C@](C(COC(CCN)=O)=O)(O)C2.Cl
Molecular Formula
C30H33ClFNO13
Molecular Weight
670.03
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Topo II
Frequently Asked Questions
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