Atevirdine (mesylate)
Atevirdine (U 87201E) mesylate is a nonnucleoside reverse transcriptase (NNRT) inhibitor. Atevirdine mesylate can inhibit human immunodeficiency virus type 1 (HIV-1) with an IC50 of 0.06-1.6 μM. Atevirdine mesylate shows highly synergistic effects against Zidovudine/Didanosine-resistant clinical isolates of HIV-1 companied with Zidovudine /Didanosine (Hy-B0249). Atevirdine mesylate can be used for the research of AIDS[1].
Product Specifications
CAS Number
138540-32-6
Product Name Alternative
U 87201E (mesylate)
UNSPSC
12352005
Target
HIV; Reverse Transcriptase
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Smiles
CS(=O)(O)=O.CCNC1=C(N2CCN(C(C3=CC4=C(C=CC(OC)=C4)N3)=O)CC2)N=CC=C1
Molecular Formula
C22H29N5O5S
Molecular Weight
475.56
References & Citations
[1]Campbell TB, et al. Inhibition of human immunodeficiency virus type 1 replication in vitro by the bisheteroarylpiperazine atevirdine (U-87201E) in combination with zidovudine or didanosine. J Infect Dis. 1993 Aug;168 (2) :318-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1
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