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Zoniporide (Standard)

Zoniporide (Standard) is the analytical standard of Zoniporide. This product is intended for research and analytical applications. Zoniporide (CP-597396) is a potent and selective NHE-1 inhibitor with cardioprotective activity. Zoniporide inhibits 22Na+ uptake by human NHE-1-expressing fibroblasts in a concentration-dependent manner (IC50=14 nM) . Zoniporide inhibits platelet swelling in vitro with an IC50 of 0.059 μM. Zoniporide can be used in the study of cardiovascular disease[1].

Product Specifications

CAS Number

[241800-98-6]

Product Name Alternative

CP-597396 (Standard)

UNSPSC

12352005

Target

Na+/H+ Exchanger (NHE) ; Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Cardiovascular Disease

Smiles

N=C(N)NC(C1=C(C2CC2)N(C3=C4C(N=CC=C4)=CC=C3)N=C1)=O

Molecular Formula

C17H16N6O

Molecular Weight

320.35

References & Citations

[1]Marala, et al. "Zoniporide: a potent and highly selective inhibitor of human Na+/H+ exchanger-1." European journal of pharmacology 451.1 (2002) : 37-41.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

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