Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Zoniporide (hydrochloride hydrate) (Standard)

Zoniporide (hydrochloride hydrate) (Standard) is the analytical standard of Zoniporide (hydrochloride hydrate) . This product is intended for research and analytical applications. Zoniporide (CP-597396) hydrochloride hydrate is a potent and selective inhibitor of sodium-hydrogen exchanger type 1 (NHE-1) . Zoniporide hydrochloride hydrate inhibits human NHE-1 (IC50=14 nM), and has >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride hydrate potently inhibits ex vivo NHE-1-dependent swelling of human platelets (IC50=59 nM) [1][2].

Product Specifications

Product Name Alternative

CP-597396 (hydrochloride hydrate) (Standard)

UNSPSC

12352005

Target

Na+/H+ Exchanger (NHE) ; Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Cardiovascular Disease

Smiles

O=C(C1=C(C2CC2)N(C3=C4C=CC=NC4=CC=C3)N=C1)NC(N)=N.[H]Cl.[H]O[H]

Molecular Formula

C17H19ClN6O2

Molecular Weight

374.82

References & Citations

[1]Tracey WR, et al. Zoniporide: a potent and selective inhibitor of the human sodium-hydrogen exchanger isoform 1 (NHE-1) . Cardiovasc Drug Rev. 2003 Spring;21 (1) :17-32.|[2]Guzman-Perez A, et al. Discovery of zoniporide: a potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility. Bioorg Med Chem Lett. 2001 Mar 26;11 (6) :803-7.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-105064DR/

Scientific Category

Reference Standards

CAS Number

[863406-85-3]

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Guinea pig Immunoglobulin G (IgG) ELISA Kit
AE60789GU-01 48 Tests

Guinea pig Immunoglobulin G (IgG) ELISA Kit

Ask
View Details
Guinea pig Immunoglobulin G (IgG) ELISA Kit
AE60789GU-02 96 Tests

Guinea pig Immunoglobulin G (IgG) ELISA Kit

Ask
View Details
Recombinant ATP synthase subunit b (atpF)
MBS1015408 Inquire

Recombinant ATP synthase subunit b (atpF)

Ask
View Details
Recombinant Human SNCA/ alpha-Synuclein Protein, His, Yeast-1mg
QP6704-ye-1mg 1mg

Recombinant Human SNCA/ alpha-Synuclein Protein, His, Yeast-1mg

Ask
View Details
IARS, NT (Isoleucyl-tRNA Synthetase Cytoplasmic, IARS1, IleRS, ILRS, IRS, FLJ20736, Isoleucine-tRNA Ligase, PRO0785) (AP)
MBS6481360-01 0.2 mL

IARS, NT (Isoleucyl-tRNA Synthetase Cytoplasmic, IARS1, IleRS, ILRS, IRS, FLJ20736, Isoleucine-tRNA Ligase, PRO0785) (AP)

Ask
View Details
IARS, NT (Isoleucyl-tRNA Synthetase Cytoplasmic, IARS1, IleRS, ILRS, IRS, FLJ20736, Isoleucine-tRNA Ligase, PRO0785) (AP)
MBS6481360-02 5x 0.2 mL

IARS, NT (Isoleucyl-tRNA Synthetase Cytoplasmic, IARS1, IleRS, ILRS, IRS, FLJ20736, Isoleucine-tRNA Ligase, PRO0785) (AP)

Ask
View Details