(Z) -SU14813
(Z) -SU14813 is an analog of SU14813. SU14813 is a multi-targeted receptor tyrosine kinases inhibitor with IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRβ and KIT[1].
Product Specifications
CAS Number
452105-23-6
UNSPSC
12352005
Target
Drug Derivative; PDGFR; VEGFR
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
O=C1NC2=CC=C(C=C2/C1=C/C3=C(C(C(NC[C@@H](CN4CCOCC4)O)=O)=C(N3)C)C)F
Molecular Formula
C23H27FN4O4
Molecular Weight
442.48
References & Citations
[1]Patyna S, et al. SU14813: a novel multiple receptor tyrosine kinase inhibitor with potent antiangiogenic and antitumor activity. Mol Cancer Ther. 2006 Jul;5 (7) :1774-82.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Frequently Asked Questions
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