YM-358 hydrate (potassium)

YM-358 hydrate potassium is an orally active angiotensin II type 1 (AT1) -receptor antagonist. YM-358 hydrate potassium can decrease cardiac volume overload. YM-358 hydrate potassium can be used for the research of cardiovascular disease, such as hypertension[1].

Product Specifications

CAS Number

[161800-08-4]

UNSPSC

12352005

Target

Angiotensin Receptor

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Smiles

CCC1=CN(N2N=C(N=C21)CC)CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5.[K].O

Molecular Formula

C22H24KN8O

Molecular Weight

455.58

References & Citations

[1]Tokioka-Akagi T, et al. Comparison of the angiotensin II type 1-receptor antagonist YM358 and the angiotensin-converting enzyme inhibitor enalapril in rats with cardiac volume overload. Jpn J Pharmacol. 2001 May;86 (1) :79-85.