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PF-573228 (Standard)

PF-573228 (Standard) is the analytical standard of PF-573228. This product is intended for research and analytical applications. PF-573228 is a potent and selective FAK inhibitor with IC50 of 4 nM for purified recombinant catalytic fragment of FAK.

Product Specifications

CAS Number

[869288-64-2]

UNSPSC

12352005

Target

Apoptosis; FAK; Reference Standards

Related Pathways

Apoptosis; Others; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

O=C1NC2=C(C=C(NC3=NC=C(C(F)(F)F)C(NCC4=CC=CC(S(=O)(C)=O)=C4)=N3)C=C2)CC1

Molecular Formula

C22H20F3N5O3S

Molecular Weight

491.49

References & Citations

[1]Slack-Davis JK, et al. Cellular characterization of a novel focal adhesion kinase inhibitor. J Biol Chem. 2007 May 18;282 (20) :14845-52.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Curated Selection

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