A 83-01 (Standard)
A 83-01 (Standard) is the analytical standard of A 83-01 (HY-10432) . This product is intended for research and analytical applications. A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I nodal receptor ALK4 and type I nodal receptor ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively[1].
Product Specifications
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Reference Standards; TGF-β Receptor
Related Pathways
Others; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
98.69
Smiles
S=C(N1N=C(C(C2=C3C=CC=CC3=NC=C2)=C1)C4=CC=CC(C)=N4)NC5=CC=CC=C5
Molecular Formula
C25H19N5S
Molecular Weight
421.52
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture, under nitrogen
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-10432R/A-83-01-Standard-SDS-MedChemExpress.pdf
Scientific Category
Reference Standards
Clinical Information
No Development Reported
Isoform
ALK4; ALK5; ALK7
CAS Number
[909910-43-6]
Available Sizes
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