North-methanocarbathymidine
North-methanocarbathymidine (N-MCT) is a potent antiviral agent. North-methanocarbathymidine inhibits DNA synthesis. North-methanocarbathymidine demonstrates potent antiviral activity against HSV-1, HSV-2 and KSHV. North-methanocarbathymidine exhibits anticancer activity against colon adenocarcinoma expressing HSV-tk[1].
Product Specifications
CAS Number
[156126-12-4]
Product Name Alternative
N-MCT
UNSPSC
12352005
Target
DNA/RNA Synthesis; HSV
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Smiles
O=C1NC(C(C)=CN1[C@@H]2[C@@]3([H])C[C@@]3(CO)[C@@H](O)C2)=O
Molecular Formula
C12H16N2O4
Molecular Weight
252.27
References & Citations
[1]Marquez VE, et al. The history of N-methanocarbathymidine: the investigation of a conformational concept leads to the discovery of a potent and selective nucleoside antiviral agent. Antiviral Res. 2006 Sep;71 (2-3) :268-75.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HSV-1; HSV-2
Curated Selection
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