Pamapimod (Standard)
Pamapimod (Standard) is the analytical standard of Pamapimod. This product is intended for research and analytical applications. Pamapimod (Ro4402257) is a potent, selective and orally active p38 MAPK inhibitor with IC50s of 14 nM and 480 nM and Kis of 1.3 nM and 120 nM for p38α and p38β, respectively. Pamapimod has no activity against p38δ or p38γ isoforms. Pamapimod has the potential for rheumatoid arthritis and other autoimmune diseases treatment[1].
Product Specifications
CAS Number
449811-01-2
Product Name Alternative
Ro4402257 (Standard) ; R1503 (Standard)
UNSPSC
12352005
Target
Autophagy; p38 MAPK; Reference Standards
Related Pathways
Autophagy; MAPK/ERK Pathway; Others
Field of Research
Inflammation/Immunology
Smiles
O=C1C(OC2=CC=C(F)C=C2F)=CC3=CN=C(NC(CCO)CCO)N=C3N1C
Molecular Formula
C19H20F2N4O4
Molecular Weight
406.38
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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