Eperezolid (Standard)

Eperezolid (Standard) is an analytical standard for Eperezolid. This product is intended for research and analytical applications. Eperezolid (PNU-100592) is an oxazolidinone antibiotic with good in vitro inhibitory properties.

Product Specifications

CAS Number

[165800-04-4]

Product Name Alternative

PNU-100592 (Standard)

UNSPSC

12352005

Target

Antibiotic; Bacterial; Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

O=C(O[C@H]1CNC(C)=O)N(C1)C2=CC(F)=C(C=C2)N3CCN(CC3)C(CO)=O

Molecular Formula

C18H23FN4O5

Molecular Weight

394.40

References & Citations

[1]Rybak MJ, et al. Comparative in vitro activities and postantibiotic effects of the oxazolidinone compounds eperezolid (PNU-100592) and linezolid (PNU-100766) versus vancomycin against Staphylococcus aureus, coagulase-negative staphylococci, Enterococcus faecalis, and Enterococcus faecium. Antimicrob Agents Chemother. 1998 Mar;42 (3) :721-4.|[2]Lin AH, et al. The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin. Antimicrob Agents Chemother. 1997 Oct;41 (10) :2127-31.|[3]Zhou CC, et al. 1H nuclear magnetic resonance study of oxazolidinone binding to bacterial ribosomes. Antimicrob Agents Chemother. 2002 Mar;46 (3) :625-9.