AP24163
AP24163 is a BCR-ABL kinase inhibitor. AP24163 inhibits wild-type (native) BCR-ABL and BCR-ABL-T315I with IC50 values of 7 nM and 511 nM, respectively. AP24163 can be used in the research of chronic myeloid leukemia (CML) [1].
Product Specifications
CAS Number
[926922-16-9]
UNSPSC
12352005
Target
Bcr-Abl
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(NC1=CC(N2C=NC(C)=C2)=CC(C(F)(F)F)=C1)C3=CC(/C=C/N4C5=NC=NC(NC6CC6)=C5N=C4)=C(C)C=C3
Molecular Formula
C29H25F3N8O
Molecular Weight
558.56
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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