(S, S, S) -AHPC-PEG2-NH2
(S, S, S) -AHPC-PEG2-NH2 is an isomer of Compound 15b. Compound 15b is a conjugate of a VHL ligand and linker. Compound 15b can be used to synthesize PROTAC. Compound 15b can be used in leukemia research[1].
Product Specifications
CAS Number
3049082-35-8
UNSPSC
12352211
Target
Drug Isomer; E3 Ligase Ligand-Linker Conjugates
Related Pathways
Others; PROTAC
Field of Research
Cancer
Smiles
O=C([C@H]1N(C([C@@H](NC(COCCOCCN)=O)C(C)(C)C)=O)C[C@@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2
Molecular Formula
C28H41N5O6S
Molecular Weight
575.72
References & Citations
[1]Zhai J, et al. Sunitinib-based Proteolysis Targeting Chimeras (PROTACs) reduced the protein levels of FLT-3 and c-KIT in leukemia cell lines. Bioorg Med Chem Lett. 2022 Dec 15;78:129041.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
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