Org 20599 (methanesulfonate)

Org20599 methanesulfonate is a direct agonist of the GABAA receptor with an EC50 of 1.1 μM. Org20599 methanesulfonate can be used in the research of neurological disorders[1].

Product Specifications

CAS Number

[187652-71-7]

UNSPSC

12352005

Target

GABA Receptor

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

CS(=O)(O)=O.C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@@H]([C@@H](N4CCOCC4)C2)O)([H])[C@@]5([H])[C@](CC3)([C@H](CC5)C(CCl)=O)C

Molecular Formula

C26H44ClNO6S

Molecular Weight

534.15

References & Citations

[1]Visser SA, et al. Neuroactive steroids differ in potency but not in intrinsic efficacy at the GABA (A) receptor in vivo. J Pharmacol Exp Ther. 2002 Nov;303 (2) :616-26.