PHTPP (Standard)
PHTPP (Standard) is the analytical standard of PHTPP. This product is intended for research and analytical applications. PHTPP is a selective estrogen receptor β (ERβ) antagonist with 36-fold selectivity over ERα[1].
Product Specifications
CAS Number
805239-56-9
UNSPSC
12352005
Target
Estrogen Receptor/ERR; Reference Standards
Related Pathways
Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
OC1=CC=C(C2=C3N=C(C(F)(F)F)C=C(C(F)(F)F)N3N=C2C4=CC=CC=C4)C=C1
Molecular Formula
C20H11F6N3O
Molecular Weight
423.31
References & Citations
[1]Ogo Y, et al. IGF-1 gene expression is differentially regulated by estrogen receptors α and β in mouse endometrial stromal cells and ovarian granulosa cells. J Reprod Dev. 2014;60 (3) :216-23. Epub 2014 Mar 25.|[2]Dennis R Compton, et al. Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity. J Med Chem. 2004 Nov 18;47 (24) :5872-93.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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