Tirbanibulin (Standard)
Tirbanibulin (Standard) is the analytical standard of Tirbanibulin. This product is intended for research and analytical applications. Tirbanibulin (KX2-391) is an inhibitor of Src that targets the peptide substrate site of Src, with GI50 of 9-60 nM in cancer cell lines.
Product Specifications
CAS Number
[897016-82-9]
Product Name Alternative
KX2-391 (Standard) ; KX-01 (Standard)
UNSPSC
12352005
Target
Microtubule/Tubulin; Reference Standards; Src
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(CC1=NC=C(C2=CC=C(OCCN3CCOCC3)C=C2)C=C1)NCC4=CC=CC=C4
Molecular Formula
C26H29N3O3
Molecular Weight
431.53
References & Citations
[1]Lau GM, et al. Expression of Src and FAK in hepatocellular carcinoma and the effect of Src inhibitors on hepatocellular carcinoma in vitro. Dig Dis Sci, 2009, 54 (7), 1465-1474.|[2]Fallah-Tafti A, et al. Thiazolyl N-benzyl-substituted acetamide derivatives: synthesis, Src kinase inhibitory and anticancer activities. Eur J Med Chem, 2011, 46 (10), 4853-4858.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Curated Selection
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