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Tirbanibulin (dihydrochloride) (Standard)

Selected Variant

HY-10340AR-01

Size: 5 mg

Tirbanibulin (dihydrochloride) (Standard) is the analytical standard of Tirbanibulin (dihydrochloride) . This product is intended for research and analytical applications. Tirbanibulin (dihydrochloride) (KX2-391 (dihydrochloride) ) is an inhibitor of Src that targets the peptide substrate site of Src, with GI50 of 9-60 nM in cancer cell lines.

Product Specifications

CAS Number

1038395-65-1

Product Name Alternative

KX2-391 (dihydrochloride) (Standard) ; KX-01 (dihydrochloride) (Standard)

UNSPSC

12352005

Target

Microtubule/Tubulin; Reference Standards; Src

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton; Others; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

O=C(CC1=NC=C(C2=CC=C(OCCN3CCOCC3)C=C2)C=C1)NCC4=CC=CC=C4.Cl.Cl

Molecular Formula

C26H31Cl2N3O3

Molecular Weight

504.45

References & Citations

[1]Lau GM, et al. Expression of Src and FAK in hepatocellular carcinoma and the effect of Src inhibitors on hepatocellular carcinoma in vitro. Dig Dis Sci, 2009, 54 (7), 1465-1474.|[2]Fallah-Tafti A, et al. Thiazolyl N-benzyl-substituted acetamide derivatives: synthesis, Src kinase inhibitory and anticancer activities. Eur J Med Chem, 2011, 46 (10), 4853-4858.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

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