1-Aminobenzotriazole (Standard)

1-Aminobenzotriazole (Standard) is the analytical standard of 1-Aminobenzotriazole. This product is intended for research and analytical applications. 1-Aminobenzotriazole is a nonspecific and irreversible inhibitor of cytochrome P450 (P450) .

Product Specifications

CAS Number

[1614-12-6]

Product Name Alternative

ABT (Standard) ; 3-Aminobenzotriazole (Standard)

UNSPSC

12352005

Target

Cytochrome P450; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

NN1N=NC2=CC=CC=C21

Molecular Formula

C6H6N4

Molecular Weight

134.14

References & Citations

[1]Yang K, et al. Induction of CYP2B6 and CYP3A4 expression by 1-aminobenzotriazole (ABT) in human hepatocytes. Drug Metab Lett. 2010 Aug;4 (3) :129-33.|[2]Sun Q, et al. 1-Aminobenzotriazole, a known cytochrome P450 inhibitor, is a substrate and inhibitor of N-acetyltransferase. Drug Metab Dispos. 2011 Sep;39 (9) :1674-9.|[3]Stringer RA, et al. 1-Aminobenzotriazole modulates oral drug pharmacokinetics through cytochrome P450 inhibition and delay of gastric emptying in rats. Drug Metab Dispos. 2014 Jul;42 (7) :1117-24.