M50054 (Standard)

M50054 (Standard) is the analytical standard of M50054. This product is intended for research and analytical applications. M50054 is a potent inhibitor of apoptosis. M50054 inhibits Etoposide-induced caspase-3 activation of U937 cells with an IC50 of 79 μg/mL. M50054 does not directly inhibit the enzymatic activity of caspase-3. M50054 can be used for the research anti-Fas-antibody-induced hepatitis and chemotherapy-induced alopecia[1].

Product Specifications

CAS Number

[54135-60-3]

UNSPSC

12352211

Target

Apoptosis; Reference Standards

Related Pathways

Apoptosis; Others

Field of Research

Inflammation/Immunology

Smiles

O=C1C(CC(C(CCC2)=O)C2=O)C(CCC1)=O

Molecular Formula

C13H16O4

Molecular Weight

236.26

References & Citations

[1]T Tsuda, et al. Inhibitory effect of M50054, a novel inhibitor of apoptosis, on anti-Fas-antibody-induced hepatitis and chemotherapy-induced alopecia. Eur J Pharmacol.2001 Dec 14;433 (1) :37-45.