2-MPPA (Standard)
2-MPPA (Standard) is the analytical standard of 2-MPPA. This product is intended for research and analytical applications. 2-MPPA (GPI-5693) is an orally active and selective glutamate carboxypeptidase II (GCP II; PSMA) inhibitor with an IC50 of 90 nM[1][2].
Product Specifications
CAS Number
254737-29-6
Product Name Alternative
GPI-5693 (Standard)
UNSPSC
12352211
Target
Carboxypeptidase; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer; Neurological Disease
Smiles
O=C(O)C(CCCS)CCC(O)=O
Molecular Formula
C8H14O4S
Molecular Weight
206.26
References & Citations
[1]Takatsu Y, et al. Orally active glutamate carboxypeptidase II inhibitor 2-MPPA attenuates dizocilpine-induced prepulse inhibition deficits in mice. Brain Res. 2011 Jan 31;1371:82-6. |[2]She Y, et al. 2-MPPA, a selective inhibitor of PSMA, delays prostate cancer growth and attenuates taxol-induced neuropathy in mice. Journal of Clinical Oncology, 2005, 23 (16_suppl) : 8054-8054.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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