N-Arachidonylglycine (Standard)

20 (S) -Ginsenoside Rg3 (Standard) is the analytical standard of 20 (S) -Ginsenoside Rg3. This product is intended for research and analytical applications. 20 (S) -Ginsenoside Rg3 is the main component of Panax ginseng C. A. Meyer. Ginsenoside Rg3 inhibits Na+ and hKv1.4 channel with IC50s of 32.2±4.5 and 32.6±2.2 μM, respectively. 20 (S) -Ginsenoside Rg3 also inhibits Aβ levels, NF-κB activity, and COX-2 expression.

Product Specifications

CAS Number

[179113-91-8]

Product Name Alternative

NA-Gly (Standard)

UNSPSC

12352211

Target

Endogenous Metabolite; GlyT; Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Field of Research

Inflammation/Immunology

Smiles

O=C(O)CNC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O

Molecular Formula

C22H35NO3

Molecular Weight

361.52

References & Citations

[1]McHugh D, et al. Δ (9) -Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells. Br J Pharmacol. 2012;165 (8) :2414-2424.|[2]Edington AR, et al. Extracellular loops 2 and 4 of GLYT2 are required for N-arachidonylglycine inhibition of glycine transport. J Biol Chem. 2009;284 (52) :36424-36430.|[3]Burstein SH. N-Acyl Amino Acids (Elmiric Acids) : Endogenous Signaling Molecules with Therapeutic Potential. Mol Pharmacol. 2018;93 (3) :228-238.