NAADP (tetrasodium)
NAADP tetrasodium is a second messenger. NAADP tetrasodium releases Ca2+ from acidic endosomes and lysosomes. NAADP tetrasodium can be used to study cancer (such as oral squamous cell carcinoma, malignant melanoma) and angiogenesis-related diseases[1].
Product Specifications
UNSPSC
12352005
Target
Calcium Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Cancer; Cardiovascular Disease
Purity
95.8
Smiles
NC1=NC=NC2=C1N=CN2[C@@H]3O[C@H](COP(OP(OC[C@H]4O[C@@H]([N+]5=CC(C(O[Na])=O)=CC=C5)[C@H](O)[C@@H]4O)(O[Na])=O)(O[Na])=O)[C@@H](O)[C@H]3OP([O-])(O[Na])=O
Molecular Formula
C21H23N6Na4O18P3
Molecular Weight
832.32
References & Citations
[1]Parrington J, et al. Calcium signals regulated by NAADP and two-pore channels--their role in development, differentiation and cancer. Int J Dev Biol. 2015;59 (7-9) :341-55.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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