Bepridil-d5 (hydrochloride)

Bepridil-d5 (hydrochloride) (CERM 1978-d5) is deuterium labeled Bepridil hydrochloride. Bepridil hydrochloride (CERM 1978) is a calcium channel blocker, with antianginal activity.

Product Specifications

Product Name Alternative

CERM 1978-d5

UNSPSC

12352005

Target

Calcium Channel; Isotope-Labeled Compounds

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Smiles

CC(COCC(CN(CC1=CC=CC=C1)C2=C(C([2H])=C(C([2H])=C2[2H])[2H])[2H])N3CCCC3)C.Cl

Molecular Formula

C24H30D5ClN2O

Molecular Weight

408.03

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Flaim SF, et al. Effects of bepridil hydrochloride on cardiocirculatory dynamics, coronary vascular resistance, and cardiac output distribution in normal, conscious rats. J Cardiovasc Pharmacol. 1988 Mar;11 (3) :363-72.