Monomethyl fumarate (Standard)
Monomethyl fumarate (Standard) is the analytical standard of Monomethyl fumarate. This product is intended for research and analytical applications. Monomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease[1][2][3].
Product Specifications
CAS Number
2756-87-8
UNSPSC
12352211
Target
Drug Metabolite; GPR109A; Reference Standards
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Others
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
O=C(OC)/C=C/C(O)=O
Molecular Formula
C5H6O4
Molecular Weight
130.10
References & Citations
[1]Tang H, et al. The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist. Biochem Biophys Res Commun. 2008 Oct 31;375 (4) :562-5.|[2]Jiang D, et al. Monomethyl Fumarate Protects the Retina From Light-Induced Retinopathy. Invest Ophthalmol Vis Sci. 2019 Mar 1;60 (4) :1275-1285.|[3]Sghaier R, et al. Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrialalterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol. J Steroid Biochem Mol Biol. 2019 Nov;194:105432.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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