TCPOBOP (Standard)
TCPOBOP (Standard) is the analytical standard of TCPOBOP. This product is intended for research and analytical applications. TCPOBOP is a constitutive androstane receptor (CAR) agonist that induces robust hepatocyte proliferation and hepatomegaly without any liver injury or tissue loss[1]. TCPOBOP attenuates Fas-induced murine liver injury by altering Bcl-2 proteins[2].
Product Specifications
CAS Number
76150-91-9
UNSPSC
12352005
Target
Bcl-2 Family; Reference Standards
Related Pathways
Apoptosis; Others
Field of Research
Cancer
Smiles
ClC1=CN=C(OC2=CC=C(OC3=NC=C(Cl)C=C3Cl)C=C2)C(Cl)=C1
Molecular Formula
C16H8Cl4N2O2
Molecular Weight
402.06
References & Citations
[1]Bhushan B, et al. TCPOBOP-Induced Hepatomegaly and Hepatocyte Proliferation are Attenuated by Combined Disruption of MET and EGFR Signaling. Hepatology. 2019 Apr;69 (4) :1702-1718.|[2]Baskin-Bey ES, et al. Constitutive androstane receptor (CAR) ligand, TCPOBOP, attenuates Fas-induced murine liver injury by altering Bcl-2 proteins. Hepatology. 2006 Jul;44 (1) :252-62.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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