SNAP5089 (hydrochloride)

SNAP5089 (hydrochloride) is a selective α1A adrenergic receptor antagonist. SNAP5089 (hydrochloride) can be used in the research of hypertension and benign prostatic hyperplasia[1][2].

Product Specifications

CAS Number

[157066-77-8]

UNSPSC

12352005

Target

Adrenergic Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Cardiovascular Disease

Smiles

O=C(C1=C(C)NC(C)=C(C(NCCCN2CCC(C3=CC=CC=C3)(C4=CC=CC=C4)CC2)=O)C1C5=CC=C([N+]([O-])=O)C=C5)OC.[H]Cl

Molecular Formula

C36H41ClN4O5

Molecular Weight

645.19

References & Citations

[1]Proudman RGW, et al. The affinity and selectivity of α-adrenoceptor antagonists, antidepressants, and antipsychotics for the human α1A, α1B, and α1D-adrenoceptors. Pharmacol Res Perspect. 2020 Aug;8 (4) :e00602.|[2]Wetzel JM, et al. Discovery of alpha 1a-adrenergic receptor antagonists based on the L-type Ca2+ channel antagonist niguldipine. J Med Chem. 1995 May 12;38 (10) :1579-81.