SB 204741 (Standard)
SB 204741 (Standard) is the analytical standard of SB 204741. This product is intended for research and analytical applications. SB 204741 is a selective and high affinity 5-HT2B antagonist with a pKi value of 7.1[1].
Product Specifications
CAS Number
152239-46-8
UNSPSC
12352005
Target
5-HT Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Cardiovascular Disease
Smiles
O=C(NC1=CC(C)=NS1)NC2=CC3=C(N(C)C=C3)C=C2
Molecular Formula
C14H14N4OS
Molecular Weight
286.35
References & Citations
[1]Bonhaus DW, et al. The pharmacology and distribution of human 5-hydroxytryptamine2B (5-HT2B) receptor gene products: comparison with 5-HT2A and 5-HT2C receptors. Br J Pharmacol. 1995;115 (4) :622-628.|[2]Bharti S, et al. 5-HT2B receptor blockade attenuates β-adrenergic receptor-stimulated myocardial remodeling in rats via inhibiting apoptosis: role of MAPKs and HSPs. Apoptosis. 2015;20 (4) :455-465.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Isoform
5-HT2 Receptor
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